Central Retinal Vein Obstruction

Terminologies

  • edema: swelling due to fluid buildup

  • Etiology: the cause or origin of disease or condition

  • ischemic: ischemic refers to a condition caused by restricted blood flow to a part of the body, usually due to blockage in blood vessels. This lack of blood flow reduces oxygen supply to tissues, which can lead to damage or dysfunction.

  • macula: The macula is the cental part of the retina, located at the back of the eye. It is responsible for sharp, detailed central vision and color perception. The macula contains a high concentration of cone photoreceptor cells, which help in recognizing fine details, such as reading, recognizing faces and seeing colors vividly.

Epidemology and Etiology

Pathophysiology

Important Clinical Signs

Differential Diagnosis

Diagnostic Evaluation

  • Intravenous fluorescein angiography: This is to inject fluorescein dye into a vein, which then travels to the blood vessels in the retina. Normally the dye fills the arteries first, then veins without delay. A delay in retinal venous filling sugests an issue with blood flow through the veins, which is commonly seen in conditions like CRVO. Intra-retinal leakage of dye means that the blood vessels are leaking fluid into the retina, which is a sign of vascular damage or breakdown of the blood-retinal barrier.

  • OCT: reveals the presence or absense of macular edema. PAMM (paracentral accute middle maculopathy, a specific OCT finding that indicates ischemia affecting the deep capillary plexus) is a sign of retinal ischemia.